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Voydeya Approved as Add-on Therapy to Treat Extravascular Haemolysis in PNH

Results showed that Voydeya met the primary endpoint of change in haemoglobin from baseline to week 12 and all key secondary endpoints.

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By: Kristin Brooks

Managing Editor, Contract Pharma

AstraZeneca’s Voydeya (danicopan) has been approved in the U.S. as add-on therapy to ravulizumab or eculizumab for the treatment of extravascular haemolysis (EVH) in adults with paroxysmal nocturnal haemoglobinuria (PNH). Voydeya is a first-in-class, oral, Factor D inhibitor developed as an add-on to standard-of-care Ultomiris (ravulizumab) or Soliris (eculizumab) to address the needs of the approximately 10-20% of patients with PNH who experience clinically significant EVH while treated w...

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